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Health Equity via Data-Guided Precision Dosing

Coarse methods for selecting drug doses can be convenient, but are they appropriate when the stakes are high?

Improving outcomes, quality-of-life and therapeutic performance, via safer and more effective drug regimens, tailored to each individual.

 DosoLogic Software Screenshot 1
Technology

Introducing DosoLogic.
A Digital Dosing Co-Pilot
Offering Patient-Centric
Recommendations On-Demand

Interpretable Dosing Insights

Empowering clinical decision support with best-practice pharmacology modelling via a user-friendly interface. This offers actionable guidance for therapy areas including oncology, anti-infectives and immunology. 

Seamless Accessiblity

User-led development and integration with prominent electronic health record systems ensures minimal impact to clinical workflows, secure data use and widespread availability at the point-of-care. 

Maximised Therapeutic Potential

Dose individualization reduces treatment risk by increasing the likelihood of achieving target therapeutic levels, maximising effect and minimising adverse events. This reduces time in hospital and improves quality of life.

How it Works

01.

Data: patient, sample, regimen info, drug & marker levels collected via EHR integration

02.

Modelling: data used to generate drug-specific pharmacology model for patient population

03.

Simulation: model is applied to treatment scenario(s) considering historic patient response

04.

Recommendation:

multiple dosing options offered alongside predicted outcome

05.

Optimisation: real-world data, continuously improves model predictive performance

About

Our Health is Personal.
Why Isn't Our Treatment?

One Size Fits All Dosing

Lack of patient-specific insight drives body weight/surface area guided dose selection. This approach does not fully consider the large differences between how patients process their medication.

Variability in Drug Exposure

Adoption of imprecise dosing labels can cause unpredictable or suboptimal drug-levels between  patient groups, limiting benefit or increasing toxicity / mortality.

Quality of Life Impact

The impact is inequitable outcomes for underpresented populations, with 1-in-4 cancer survivors suffering from disease related side effects, costing care providers >$500bn per year.

Partners

Backed by

Newcastle University Centre for Cancer Logo
KQ Labs Accelerator Logo
LifeArc Logo
Grow London Logo
O2H Ventures Logo
UKRI Logo
NIHR Logo
SFC Capital Logo

Hear from future adopters

Pamela Kearns

Professor of Clinical Paediatric Oncology,

University of Birmingham 

“DosoLogic will allow us to individualise the dose of chemotherapy

to maximise effect on the tumour while

minimising the short and long term side effects.”

Leadership

Meet those building the best-in-class precision dosing platform, increasing the likelihood of therapeutic success and driving equity in health outcomes across multiple disease areas.  

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